Eno1 - enolase 1, alpha non-neuron Gene

Also Known as NNE; Eno-1; MBP-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13806

Summary

Enables RNA binding activity and phosphopyruvate hydratase activity. Acts upstream of or within cellular response to interleukin-7; in utero embryonic development; and positive regulation of binding activity. Is extrinsic component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human ENO1 (Enolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Eno1 Products (3)

mRNA Protein Name
NM_001379127.1 NP_001366056.1 alpha-enolase isoform 1
NM_001379128.1 NP_001366057.1 alpha-enolase isoform 2
NM_023119.2 NP_075608.2 alpha-enolase isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
21936910 MGI
enables phosphopyruvate hydratase activity IDA
IDA: Inferred from direct assay
7323947 MGI
enables phosphopyruvate hydratase activity IMP
IMP: Inferred from mutant phenotype
30679508 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23446454 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to acid chemical IDA
IDA: Inferred from direct assay
17690254 MGI
acts upstream of or within cellular response to interleukin-7 IDA
IDA: Inferred from direct assay
29581031 MGI
involved in gluconeogenesis IMP
IMP: Inferred from mutant phenotype
30679508 MGI
involved in glycolytic process IDA
IDA: Inferred from direct assay
23446454 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
9626503 MGI
acts upstream of or within positive regulation of binding IMP
IMP: Inferred from mutant phenotype
17690254 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
17690254 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
23512986 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-enolase

  • 2-phospho-D-glycerate hydro-lyase

  • 2-phospho-D-glycerate hydrolase

  • c-Myc promoter binding protein

  • non-neural enolase

Recombinant Eno1 Proteins

Cat. No. Product Name Accession Purity
HY-P72182 Enolase 1/ENO1 Protein, Mouse (His) P17182 (S2-A433) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108868 Mersalyl Inducer 89.25% Unkown

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-131904 POMHEX 99.54% Unkown
HY-117778 SF2312 Inhibitor 95.0% Unkown
HY-131904A Hex Inhibitor 99.07% Unkown
HY-102062 Nω-Propyl-L-arginine Inhibitor 98.31% Unkown
HY-102062A Nω-Propyl-L-arginine hydrochloride Inhibitor 99.88% Unkown
HY-179578 SU212 / Unkown
HY-117778B SF2312 ammonium Inhibitor 98.0% Unkown
HY-RS16574 Eno1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-162168 Anti-inflammatory agent 71 Inhibitor / Unkown
HY-RS04378 ENO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23007 Eno1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991972 Anti-ENO1 Antibody Inhibitor / Unkown
HY-P991973 HuL001 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eno1 NCBI NCBI:2023