ASB15 - ankyrin repeat and SOCS box containing 15 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 142685

About ASB15

Cytogenetic location: 7q31.32 Genomic coordinates (GRCh38): 7:123,567,008-123,639,481 (from NCBI)

This gene has 6 transcripts (splice variants), 271 orthologues and 7 paralogues. Biased expression in heart (RPKM 6.0), kidney (RPKM 2.1) and 2 other tissues.

Summary

This gene encodes a member of the suppressor of cytokine signaling box superfamily. The proteins in this superfamily participate in the ubiquitin-proteasome system for the degradation of proteins in the cell cycle and signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

ASB15 Products (2)

mRNA Protein Name
NM_001290258.2 NP_001277187.1 ankyrin repeat and SOCS box protein 15
NM_080928.4 NP_563616.3 ankyrin repeat and SOCS box protein 15

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ASB15 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (115 - 207)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (214 - 297)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (313 - 407)

SOCS_box

SOCS_box: SOCS box (534 - 576)

  • 0
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  • 500
  • 588 a.a.
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 15

  • epididymis secretory sperm binding protein

ASB15 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ASB15 Q8WXK1 GPSM3 Homo sapiens Q9Y4H4
Validated Y2H
32296183
Intra
ASB15 Q8WXK1 ZNF587 Homo sapiens Q96SQ5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01064 ASB15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ASB15 RGD RGD:727860
Felis catus ASB15 VGNC VGNC:69352
Bos taurus ASB15 VGNC VGNC:26192
Canis familiaris ASB15 VGNC VGNC:38159
Macaca mulatta ASB15 VGNC VGNC:80795
Mus musculus ASB15 MGD MGI:1926160
Others ASB15 NCBI