SPINDOC - spindlin interactor and repressor of chromatin binding Gene

Also Known as C11orf84; SPIN-DOC

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 144097

About SPINDOC

This gene has 3 transcripts (splice variants) and 93 orthologues. Broad expression in testis (RPKM 9.7), placenta (RPKM 7.2) and 23 other tissues.

Summary

Involved in negative regulation of transcription, DNA-templated. [provided by Alliance of Genome Resources, Apr 2022]

SPINDOC Products (1)

mRNA Protein Name
NM_138471.3 NP_612480.1 spindlin interactor and repressor of chromatin-binding protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IDA
IDA: Inferred from direct assay
34737271 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IDA
IDA: Inferred from direct assay
34737271 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
29061846 GOA
involved in regulation of protein ADP-ribosylation IDA
IDA: Inferred from direct assay
34737271 GOA
Cellular Component GO Annotation Evidence References Source
is active in nucleus IDA
IDA: Inferred from direct assay
29061846 GOA
is active in site of DNA damage IDA
IDA: Inferred from direct assay
34737271 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spindlin interactor and repressor of chromatin-binding protein

  • SPIN1 docking protein

SPINDOC Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SPINDOC Q9BUA3 UQCRC1 Homo sapiens P31930
Validated Y2H
32814053
Intra
SPINDOC Q9BUA3 UQCRC1 Homo sapiens P31930
Y2H Array
32814053
Intra
SPINDOC Q9BUA3 UQCRC1 Homo sapiens P31930
Y2H Pooling
32814053
Intra
SPINDOC Q9BUA3 SPIN3 Homo sapiens Q5JUX0
Anti Tag CoIP
33961781
Intra
SPINDOC Q9BUA3 SPIN3 Homo sapiens Q5JUX0
Anti Tag CoIP
28514442
Intra
SPINDOC Q9BUA3 PIAS2 Homo sapiens O75928-2
Y2H Prey Pooling
32296183
Intra
SPINDOC Q9BUA3 PIAS2 Homo sapiens O75928-2
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Chondroid Lipoma
Soft Tissue Chondroma

  • Extraskeletal Chondroma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13678 SPINDOC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SPINDOC MGD MGI:2147611
Rattus norvegicus SPINDOC RGD RGD:1308106
Bos taurus SPINDOC VGNC VGNC:50753
Felis catus SPINDOC VGNC VGNC:65639
Macaca mulatta SPINDOC VGNC VGNC:77987
Others SPINDOC NCBI