WIPF2 - WAS/WASL interacting protein family member 2 Gene

Also Known as WICH; WIRE

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 147179

Summary

This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin Cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the Actin polymerization machinery. [provided by RefSeq, Jul 2008]
Ubiquitous expression in brain (RPKM 10.6), colon (RPKM 7.8) and 25 other tissues.

WIPF2 Products (1)

mRNA Protein Name
NM_133264.5 NP_573571.1 WAS/WASL-interacting protein family member 2
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20936779 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WIPF2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
WIPF2 Q8TF74 TVP23A Homo sapiens A6NH52 32296183
Intra
WIPF2 Q8TF74 TVP23A Homo sapiens A6NH52 32296183
Intra
WIPF2 Q8TF74 GRB2 Homo sapiens P62993 20936779
Intra
WIPF2 Q8TF74 GRB2 Homo sapiens P62993
Y2H
21988832
Intra
WIPF2 Q8TF74 SORBS3 Homo sapiens O60504 32296183
Intra
WIPF2 Q8TF74 SORBS3 Homo sapiens O60504 32296183
Intra
WIPF2 Q8TF74 WASL Homo sapiens O00401 35271311
Intra
WIPF2 Q8TF74 WASL Homo sapiens O00401 32296183
Intra
WIPF2 Q8TF74 WASL Homo sapiens O00401 32296183
Cross: Cross-species interaction Intra: Intraspecies interaction