SEPTIN10 - septin 10 Gene

Also Known as SEPT10; Septin-10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 151011

Summary

This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
Ubiquitous expression in esophagus (RPKM 22.6), testis (RPKM 22.2) and 24 other tissues.

SEPTIN10 Products (21)

mRNA Protein Name
NM_001321496.2 NP_001308425.1 septin-10 isoform 3
NM_001321498.2 NP_001308427.1 septin-10 isoform 4
NM_001321499.2 NP_001308428.1 septin-10 isoform 5
NM_001321500.2 NP_001308429.1 septin-10 isoform 6
NM_001321501.2 NP_001308430.1 septin-10 isoform 7
NM_001321502.2 NP_001308431.1 septin-10 isoform 8
NM_001321503.2 NP_001308432.1 septin-10 isoform 9
NM_001321504.2 NP_001308433.1 septin-10 isoform 10
NM_001321505.2 NP_001308434.1 septin-10 isoform 11
NM_001321506.2 NP_001308435.1 septin-10 isoform 12
NM_001321507.2 NP_001308436.1 septin-10 isoform 13
NM_001321508.2 NP_001308437.1 septin-10 isoform 14
NM_001321509.2 NP_001308438.1 septin-10 isoform 15
NM_001321510.2 NP_001308439.1 septin-10 isoform 16
NM_001321511.2 NP_001308440.1 septin-10 isoform 17
NM_001321512.2 NP_001308441.1 septin-10 isoform 18
NM_001321513.2 NP_001308442.1 septin-10 isoform 19
NM_001321514.2 NP_001308443.1 septin-10 isoform 20
NM_001321515.2 NP_001308444.1 septin-10 isoform 21
NM_144710.5 NP_653311.1 septin-10 isoform 1
NM_178584.4 NP_848699.1 septin-10 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SEPTIN10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SEPTIN10 Q9P0V9 SEPTIN7 Homo sapiens Q16181-2
Y2H Prey Pooling
25416956
Intra
SEPTIN10 Q9P0V9 SEPTIN7 Homo sapiens Q16181-2
Validated Y2H
25416956
Intra
SEPTIN10 Q9P0V9 SEPTIN7 Homo sapiens Q16181
Crosslink
30021884
Intra
SEPTIN10 Q9P0V9 SEPTIN7 Homo sapiens Q16181
Anti Tag CoIP
33961781
Intra
SEPTIN10 Q9P0V9 SEPTIN5 Homo sapiens Q99719
Y2H Prey Pooling
25416956
Intra
SEPTIN10 Q9P0V9 SEPTIN5 Homo sapiens Q99719
Anti Tag CoIP
33961781
Intra
SEPTIN10 Q9P0V9 SEPTIN5 Homo sapiens Q99719
Validated Y2H
25416956
Intra
SEPTIN10 Q9P0V9 SEPTIN5 Homo sapiens Q99719
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12681 SEPTIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown