PEBP4 - phosphatidylethanolamine binding protein 4 Gene

Also Known as CORK1; CORK-1; PEBP-4; hPEBP4; PRO4408; GWTM1933; HEL-S-300

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 157310

About PEBP4

Cytogenetic location: 8p21.3 Genomic coordinates (GRCh38): 8:22,713,251-22,941,077 (from NCBI)

This gene has 3 transcripts (splice variants), 157 orthologues and 2 paralogues. Biased expression in lung (RPKM 23.8), heart (RPKM 14.9) and 5 other tissues.

Summary

The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]

PEBP4 Products (2)

mRNA Protein Name
NM_001363233.2 NP_001350162.1 phosphatidylethanolamine-binding protein 4 precursor
NM_144962.3 NP_659399.2 phosphatidylethanolamine-binding protein 4 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19197339 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PEBP4 Protein Structure

PBP

PBP: Phosphatidylethanolamine-binding protein (86 - 195)

  • 0
  • 100
  • 200
  • 227 a.a.
Protein Preferred Names Protein Names

phosphatidylethanolamine-binding protein 4

  • cousin-of-RKIP 1 protein

PEBP4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PEBP4 Q96S96 AKT1 Homo sapiens P31749
Anti Bait CoIP
19197339
Intra
PEBP4 Q96S96 AKT1 Homo sapiens P31749
Anti Tag CoIP
19197339
Intra
PEBP4 Q96S96 RAF1 Homo sapiens P04049
Anti Bait CoIP
19197339
Intra
PEBP4 Q96S96 RAF1 Homo sapiens P04049
Anti Tag CoIP
19197339
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10314 PEBP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PEBP4 VGNC VGNC:32736
Macaca mulatta PEBP4 VGNC VGNC:82204
Mus musculus PEBP4 MGD MGI:1920773
Rattus norvegicus PEBP4 RGD RGD:1593295
Canis familiaris PEBP4 VGNC VGNC:44409
Felis catus PEBP4 VGNC VGNC:79361
Others PEBP4 NCBI