Jchain - immunoglobulin joining chain Gene

Also Known as Igj; Jch; 9530090F24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16069

Summary

Enables IgA binding activity and protein-macromolecule adaptor activity. Contributes to immunoglobulin receptor binding activity. Predicted to be involved in several processes, including defense response to Other organism; glomerular filtration; and positive regulation of respiratory burst. Part of dimeric IgA immunoglobulin complex. Is expressed in intestine; serum; and spleen. Orthologous to human JCHAIN (joining chain of multimeric IgA and IgM). [provided by Alliance of Genome Resources, Apr 2022]

Jchain Products (1)

mRNA Protein Name
NM_152839.4 NP_690052.2 immunoglobulin J chain precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables IgA binding IDA
IDA: Inferred from direct assay
17237408 MGI
contributes to immunoglobulin receptor binding IMP
IMP: Inferred from mutant phenotype
17237408 MGI
enables protein-macromolecule adaptor activity IDA
IDA: Inferred from direct assay
17237408 MGI
Cellular Component GO Annotation Evidence References Source
part of dimeric IgA immunoglobulin complex IMP
IMP: Inferred from mutant phenotype
17237408 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immunoglobulin J chain

  • immunoglobulin joining gene (not J region)

Recombinant Jchain Proteins

Cat. No. Product Name Accession Purity
HY-P71744 Immunoglobulin J chain Protein, Mouse (P.pastoris, His) P01592 (G22-D159) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P4062 Insulin peglispro / Phase 3

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P3479 Insulin (swine) 99.90% Unkown
HY-P3432 DfTat 99.53% Unkown
HY-P4890A Relaxin H3 (human) TFA / Unkown
HY-P10204 FZD7 antagonist 1 / Unkown
HY-P10693 CZEN-002 Inhibitor / Unkown
HY-P11246 A13:B7-24-GG Agonist / Unkown
HY-P11548 Rattusin Inhibitor / Unkown
HY-P11625 R9-13 Activator / Unkown
HY-P11823 FAPα/DPP4 flurogenic substrate-1 / Unkown
HY-P1371 Pseudo RACK1 Agonist / Unkown
HY-P1372 PKC ζ pseudosubstrate Inhibitor / Unkown
HY-P4890 Relaxin H3 (human) / Unkown
HY-RS07033 JCHAIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17925 Jchain Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24395 Jchain Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jchain NCBI NCBI:3512