ZNF467 - zinc finger protein 467 Gene

Also Known as EZI; Zfp467

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 168544

About ZNF467

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:149,764,182-149,776,530 (from NCBI)

This gene has 2 transcripts (splice variants), 90 orthologues and 51 paralogues. Ubiquitous expression in spleen (RPKM 2.9), kidney (RPKM 2.5) and 25 other tissues.

Summary

The protein encoded by this gene is a Zinc Finger Protein whose function has not yet been elucidated in humans. However, the mouse ortholog of this protein enhances adipocyte differentiation and suppresses osteoblast differentiation in bone marrow. The mouse protein also is a transcription factor for several genes and can help recruit histone deacetylase complexes. [provided by RefSeq, Aug 2016]

ZNF467 Products (2)

mRNA Protein Name
NM_001329856.2 NP_001316785.1 zinc finger protein 467 isoform 2
NM_207336.3 NP_997219.1 zinc finger protein 467 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF467 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (175 - 198)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (206 - 226)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (230 - 254)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (261 - 282)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (286 - 311)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (355 - 377)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (445 - 469)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (487 - 509)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (529 - 554)

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  • 500
  • 595 a.a.
Protein Preferred Names Protein Names

zinc finger protein 467

  • zinc finger protein EZI

ZNF467 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF467 Q7Z7K2 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
ZNF467 Q7Z7K2 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
ZNF467 Q7Z7K2 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra
ZNF467 Q7Z7K2 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra
ZNF467 Q7Z7K2 L3MBTL2 Homo sapiens Q969R5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16145 ZNF467 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZNF467 VGNC VGNC:37281
Rattus norvegicus ZNF467 RGD RGD:1561603
Canis familiaris ZNF467 VGNC VGNC:48735
Mus musculus ZNF467 MGD MGI:1916160
Felis catus ZNF467 VGNC VGNC:80763
Others ZNF467 NCBI