ZNF675 - zinc finger protein 675 Gene

Also Known as TIZ; TBZF

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 171392

Summary

Enables ubiquitin protein Ligase binding activity. Involved in negative regulation of osteoclast differentiation; negative regulation of signal transduction; and negative regulation of transcription by RNA polymerase II. Located in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in lymph node (RPKM 3.0), testis (RPKM 2.9) and 24 other tissues.

ZNF675 Products (1)

mRNA Protein Name
NM_138330.3 NP_612203.2 zinc finger protein 675

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11751921 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
11751921 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of JNK cascade IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of JUN kinase activity IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of NF-kappaB transcription factor activity IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of cytokine-mediated signaling pathway IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of interleukin-1-mediated signaling pathway IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of osteoclast differentiation IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of transcription regulatory region DNA binding IDA
IDA: Inferred from direct assay
11751921 GOA
involved in negative regulation of tumor necrosis factor-mediated signaling pathway IDA
IDA: Inferred from direct assay
11751921 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11751921 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
11751921 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF675 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF675 Q8TD23 TRAF6 Homo sapiens Q9Y4K3
Pull Down
11751921
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16438 ZNF605 Human Pre-designed siRNA Set A Pre-designed Set / Unkown