AFM - afamin Gene

Homo sapiens

Also known as ALF; ALB2; ALBA

Gene ID: 173 | Gene type: protein coding

About AFM

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:73,481,745-73,504,001 (from NCBI)

This gene has 2 transcripts (splice variants), 135 orthologues and 3 paralogues. Restricted expression toward liver (RPKM 187.4).

Summary

This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream. [provided by RefSeq, Jul 2008]

AFM Products(1)

mRNA	Protein	Name
NM_001133.2	NP_001124.1	afamin precursor

AFM Protein Structure

Serum_albumin

0
100
200
300
400
500
599 a.a.

Protein Preferred Names

Protein Names

afamin

alpha-Alb

Recombinant AFM Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70036	Afamin/AFM Protein, Human (HEK293, His)	P43652 (L22-N599)	≥95%
HY-P70036A	Afamin/AFM Protein, Human (599a.a, HEK293, His)	P43652 (M1-N599)	≥95%
HY-P70036B	Afamin/AFM Protein, Human (578a.a, HEK293, C-His)	P43652 (L13-N599)	≥95%

Related Diseases

Diseases

Alias

Squamous Papillomatosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-125099A	AFM-30a hydrochloride	Inhibitor	99.96%	Unkown
HY-136557A	AFM32a hydrochloride	Inhibitor	99.71%	Unkown
HY-N0638	Dendrobine	Inhibitor	99.92%	Unkown
HY-125099	AFM-30a	Inhibitor	≥96.0%	Unkown
HY-136557	AFM32a	Inhibitor	/	Unkown
HY-D0029	5(6)-Aminofluorescein		98.09%	Unkown
HY-RS00433	AFM Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	AFM	VGNC	VGNC:69740
Bos taurus	AFM	VGNC	VGNC:25715
Canis familiaris	AFM	VGNC	VGNC:37691
Mus musculus	AFM	MGD	MGI:2429409
Rattus norvegicus	AFM	RGD	RGD:628614
Others	AFM	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.