Igbp1 - immunoglobulin (CD79A) binding protein 1 Gene

Also Known as p52; Pc52; Tap42

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18518

Summary

Enables mitogen-activated protein kinase kinase binding activity and protein domain specific binding activity. Involved in negative regulation of protein dephosphorylation; positive regulation of dephosphorylation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of apoptotic signaling pathway. Located in cytoplasm and microtubule. Is expressed in bladder; female associated reproductive structure; ovary; ureter; and urethra of female. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to human IGBP1 (immunoglobulin binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Igbp1 Products (1)

mRNA Protein Name
NM_008784.3 NP_032810.4 immunoglobulin-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
11806752 MGI
enables mitogen-activated protein kinase kinase binding IPI
IPI: Inferred from physical interaction
17438131 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12963337 MGI
enables protein domain specific binding IDA
IDA: Inferred from direct assay
11806752 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
15499020 MGI
involved in positive regulation of dephosphorylation IMP
IMP: Inferred from mutant phenotype
15499020 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
15499020 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11806752 MGI
located in microtubule IGI
IGI: Inferred from genetic interaction
11806752 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immunoglobulin-binding protein 1

  • CD79a-binding protein 1

  • alpha 4

  • alpha4 phosphoprotein

  • lymphocyte signal transduction molecule alpha 4

  • phosphoprotein, component, 52 kDa

  • protein phosphatase 2/4/6 regulatory subunit

Igbp1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Igbp1 Q61249 Ppp2ca Mus musculus P63330
Anti Bait CoIP
19818709
Cross
Igbp1 Q61249 PPP2CA Homo sapiens P67775
CoIP
12963337
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06612 IGBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igbp1 NCBI NCBI:3476