2. Gene
  3. Prkd1 - protein kinase D1 Gene

Prkd1 - protein kinase D1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PKD; PKD1; Pkcm; Prkcm; nPKC-D1; nPKC-mu

Gene ID: 18760 | Gene type: protein coding

About Prkd1

Chromosome 12: 50,388,014-50,695,881 reverse strand.GRCm39:CM001005.3

This gene has 1 transcript (splice variant), 208 orthologues, 2 paralogues and is associated with 12 phenotypes. Ubiquitous expression in genital fat pad adult (RPKM 3.1), subcutaneous fat pad adult (RPKM 2.4) and 26 other tissues.

Summary

Predicted to enable identical protein binding activity and protein kinase C activity. Involved in several processes, including positive regulation of osteoblast differentiation; positive regulation of protein import into nucleus; and regulation of keratinocyte proliferation. Acts upstream of or within regulation of release of sequestered calcium ion into cytosol. Located in several cellular components, including cell cortex; cell-cell junction; and trans-Golgi network. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and sensory organ. Orthologous to human PRKD1 (protein kinase D1). [provided by Alliance of Genome Resources, Apr 2022]

Prkd1 Products(4)

mRNA Protein Name
NM_001382816.1 NP_001369745.1 serine/threonine-protein kinase D1 isoform 4
NM_001382815.1 NP_001369744.1 serine/threonine-protein kinase D1 isoform 3
NM_001382814.1 NP_001369743.1 serine/threonine-protein kinase D1 isoform 2
NM_008858.4 NP_032884.2 serine/threonine-protein kinase D1 isoform 1

Prkd1 Protein Structure

C1_PKD1_rpt1

C1_PKD1_rpt1: cd20839 (137 - 208)

C1_PKD1_rpt2

C1_PKD1_rpt2: cd20842 (242 - 335)

PH_PKD

PH_PKD: cd01239 (421 - 548)

STKc_PKD

STKc_PKD: cd14082 (584 - 843)

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  • 918 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase D1

protein kinase C mu type

protein kinase C, mu

protein kinase D

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11144 PRKD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11145 Prkd1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11146 Prkd1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkd1 NCBI NCBI:5587