Plekhh2 - pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 Gene

Also Known as mKIAA2028; E030001K05

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213556

Summary

Enables actin binding activity. Involved in negative regulation of actin filament depolymerization. Located in cortical actin Cytoskeleton. Is expressed in s-shaped body. Orthologous to human PLEKHH2 (pleckstrin homology, MyTH4 and FERM domain containing H2). [provided by Alliance of Genome Resources, Apr 2022]

Plekhh2 Products (3)

mRNA Protein Name
NM_001357986.1 NP_001344915.1 pleckstrin homology domain-containing family H member 2 isoform 1
NM_001357987.1 NP_001344916.1 pleckstrin homology domain-containing family H member 2 isoform 2
NM_177606.4 NP_808274.2 pleckstrin homology domain-containing family H member 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
22832517 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22832517 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of actin filament depolymerization IDA
IDA: Inferred from direct assay
22832517 MGI
Cellular Component GO Annotation Evidence References Source
located in cortical actin cytoskeleton IDA
IDA: Inferred from direct assay
22832517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pleckstrin homology domain-containing family H member 2

Plekhh2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Plekhh2 Q8C115 Tgfb1i1 Mus musculus Q62219
Anti Tag CoIP
22832517
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10696 PLEKHH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plekhh2 NCBI NCBI:130271