Thbd - thrombomodulin Gene

Also Known as TM; CD141

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21824

Summary

Predicted to enable calcium ion binding activity and transmembrane signaling receptor activity. Acts upstream of or within female pregnancy. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; lung; and skeleton. Used to study thrombophilia. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin). [provided by Alliance of Genome Resources, Apr 2022]

Thbd Products (1)

mRNA Protein Name
NM_009378.3 NP_033404.1 thrombomodulin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within embryo development IMP
IMP: Inferred from mutant phenotype
7846065 MGI
acts upstream of or within female pregnancy IMP
IMP: Inferred from mutant phenotype
7846065 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
19299737 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thrombomodulin

  • fetomodulin

  • snoRNA MBII-339

Recombinant Thbd Proteins

Cat. No. Product Name Accession Purity
HY-P72451 Thrombomodulin Protein, Mouse (HEK293, His) P15306 (L17-S517) ≥ 95%, as determined by reducing SDS-PAGE.

Thbd Antibodies

Cat. No. Product Name Application Reactivity
HY-P81046 Thrombomodulin Antibody (YA892) WB Mouse, Rat
HY-P81046A Thrombomodulin Antibody (YA892)(PBS only) WB Mouse, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14478 THBD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18261 Thbd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24740 Thbd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Thbd NCBI NCBI:7056