Tpo - thyroid peroxidase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22018

Summary

This gene encodes a membrane-bound glycoprotein. The encoded enzyme plays a central role in thyroid gland function. The enzyme functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid Hormones, thyroxine and triiodothyronine. Mice with homozygous missense mutations in this gene exhibit hypothyroid dwarfism and hearing impairment. [provided by RefSeq, Sep 2015]

Tpo Products (1)

mRNA Protein Name
NM_009417.3 NP_033443.1 thyroid peroxidase precursor
Protein Preferred Names Protein Names

thyroid peroxidase

Recombinant Tpo Proteins

Cat. No. Product Name Accession Purity
HY-P78045 TPO/Thyroid Peroxidase Protein, Mouse (HEK293, His) P35419 (G32-R834) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13463 Avatrombopag Agonist 99.83% Yes
HY-19883 Lusutrombopag Agonist 98.05% Unkown
HY-W017113 2-Mercaptobenzothiazole 99.85% Yes
HY-13463A Avatrombopag maleate 99.99% Yes
HY-13463B Avatrombopag hydrochloride Agonist 97.05% Yes

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-145581 Mitiperstat Inhibitor 99.12% Phase 3

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148748 Butyzamide Activator 99.83% Unkown
HY-W017894 TPO-L 99.77% Unkown
HY-112486 TA-316 99.50% Unkown
HY-112486G TA-316 (GMP) Agonist / Unkown
HY-100380 TPO agonist 1 Agonist 98.0% Unkown
HY-148748G Butyzamide (GMP) Activator / Unkown
HY-139915 MPO-IN-1 Inhibitor 98.07% Unkown
HY-15306S Eltrombopag-13C4 97.89% Unkown
HY-19883S Lusutrombopag-d13 Agonist 98.64% Unkown
HY-13463BS Avatrombopag-d8 hydrochloride Agonist / Unkown
HY-145581B (rac)-Mitiperstat Inhibitor 98.25% Unkown
HY-145581S Mitiperstat-d3 Inhibitor / Unkown
HY-147691 MPO-IN-5 Inhibitor / Unkown
HY-153239 Eltrombopag methyl ester Agonist / Unkown
HY-RS14498 THPO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14941 TPO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16596 Tpo Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17819 Thpo Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23030 Tpo Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990685 Romiplostim Agonist ≥99.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpo NCBI NCBI:7173