Brd1 - bromodomain containing 1 Gene

Also Known as mKIAA4191; 1110059H06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223770

Summary

Predicted to enable histone binding activity. Involved in histone H3-K14 acetylation and positive regulation of erythrocyte differentiation. Part of histone H3-K14 acetyltransferase complex. Is expressed in brain; genitourinary system; and olfactory epithelium. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Orthologous to human BRD1 (bromodomain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Brd1 Products (1)

mRNA Protein Name
NM_001033274.3 NP_001028446.2 bromodomain-containing protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone reader activity IDA
IDA: Inferred from direct assay
21753189 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
21753189 MGI
Cellular Component GO Annotation Evidence References Source
part of histone H3-K14 acetyltransferase complex IDA
IDA: Inferred from direct assay
21753189 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bromodomain-containing protein 1

  • bromodomain and PHD finger-containing protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19537 NI-57 Inhibitor 99.42% Unkown
HY-13959 MS436 Inhibitor 99.94% Unkown
HY-18665 GSK-5959 Inhibitor 99.73% Unkown
HY-111875 SNIPER(BRD)-1 Inhibitor 99.68% Unkown
HY-RS01596 BRD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100670 Olinone Inhibitor / Unkown
HY-122626 BRPF1B/TRIM24-IN-1 Inhibitor / Unkown
HY-RS18339 Brd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24818 Brd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brd1 NCBI NCBI:23774