Vps18 - VPS18 CORVET/HOPS core subunit Gene

Also Known as 9930024E13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 228545

Summary

Enables actin binding activity. Acts upstream of or within endosome organization and viral entry into host cell. Located in actin filament and early endosome. Part of AP-3 adaptor complex and CORVET complex. Is expressed in alimentary system; ganglia; nose; and peripheral nervous system. Orthologous to human VPS18 (VPS18 core subunit of CORVET and HOPS complexes). [provided by Alliance of Genome Resources, Apr 2022]

Vps18 Products (1)

mRNA Protein Name
NM_172269.3 NP_758473.3 vacuolar protein sorting-associated protein 18 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
14668490 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14668490 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within endosome organization IDA
IDA: Inferred from direct assay
14668490 MGI
acts upstream of or within symbiont entry into host cell IMP
IMP: Inferred from mutant phenotype
24550300 MGI
Cellular Component GO Annotation Evidence References Source
part of AP-3 adaptor complex IDA
IDA: Inferred from direct assay
21411634 MGI
part of CORVET complex IDA
IDA: Inferred from direct assay
25266290 MGI
located in actin filament IDA
IDA: Inferred from direct assay
14668490 MGI
located in early endosome IDA
IDA: Inferred from direct assay
14668490 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 18 homolog

  • vacuolar protein sorting 18

Vps18 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Vps18 Q8R307 VIPAS39 Homo sapiens Q9H9C1
Anti Tag CoIP
19109425
Cross
Vps18 Q8R307 VIPAS39 Homo sapiens Q9H9C1
Anti Bait CoIP
19109425
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15677 VPS18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21082 Vps18 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27599 Vps18 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps18 NCBI NCBI:57617