AKR7A3 - aldo-keto reductase family 7 member A3 Gene

Homo sapiens

Also known as AFAR2

Gene ID: 22977 | Gene type: protein coding

About AKR7A3

Cytogenetic location: 1p36.13 Genomic coordinates (GRCh38): 1:19,274,229-19,288,770 (from NCBI)

This gene has 1 transcript (splice variant), 490 orthologues and 16 paralogues. Biased expression in duodenum (RPKM 81.0), small intestine (RPKM 50.3) and 6 other tissues.

Summary

Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]

AKR7A3 Products(1)

mRNA	Protein	Name
NM_012067.3	NP_036199.2	aflatoxin B1 aldehyde reductase member 3

AKR7A3 Protein Structure

Aldo_ket_red

0
100
200
300
331 a.a.

Protein Preferred Names

Protein Names

aflatoxin B1 aldehyde reductase member 3

AFB1 aldehyde reductase 2

Related Diseases

Diseases

Alias

Cytochrome P450 Oxidoreductase Deficiency

Por Deficiency	Pord
Antley-Bixler Syndrome With Disordered Steroidogenesis	Antley-Bixler Syndrome
Antley-Bixler Syndrome-Like Phenotype With Disordered Steroidogenesis	Combined Partial Deficiency Of 17-Hydroxylase And 21-Hydroxylase
Congenital Adrenal Hyperplasia Due To Apparent Combined P450c17 And P450c21 Deficiency	Antley-Bixler Syndrome, Autosomal Dominant

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00541	AKR7A3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	AKR7A3	MGD	MGI:107796
Rattus norvegicus	AKR7A3	RGD	RGD:628635

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