2. Gene
  3. SAMD4A - sterile alpha motif domain containing 4A Gene

SAMD4A - sterile alpha motif domain containing 4A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SMG; SMGA; SAMD4; SMAUG; SMAUG1

Gene ID: 23034 | Gene type: protein coding

About SAMD4A

Cytogenetic location: 14q22.2 Genomic coordinates (GRCh38): 14:54,565,316-54,793,315 (from NCBI)

This gene has 15 transcripts (splice variants), 209 orthologues and 1 paralogue. Broad expression in testis (RPKM 19.6), heart (RPKM 19.4) and 22 other tissues.

Summary

Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]

SAMD4A Products(3)

mRNA Protein Name
NM_001161576.2 NP_001155048.2 protein Smaug homolog 1 isoform 2
NM_001161577.2 NP_001155049.1 protein Smaug homolog 1 isoform 3
NM_015589.6 NP_056404.4 protein Smaug homolog 1 isoform 1

SAMD4A Protein Structure

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (325 - 381)

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  • 718 a.a.
Protein Preferred Names Protein Names

protein Smaug homolog 1

SAM domain-containing protein 4A

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12426 SAMD4A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SAMD4A VGNC VGNC:80853
Macaca mulatta SAMD4A VGNC VGNC:77085
Mus musculus SAMD4A MGD MGI:1921730
Rattus norvegicus SAMD4A RGD RGD:1310361
Canis familiaris SAMD4A VGNC VGNC:45852
Bos taurus SAMD4A VGNC VGNC:34272