TSPAN15 - tetraspanin 15 Gene

Also Known as NET7; NET-7; TM4SF15; 2700063A19Rik

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23555

About TSPAN15

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:69,451,465-69,549,508 (from NCBI)

This gene has 8 transcripts (splice variants), 204 orthologues and 32 paralogues. Broad expression in fat (RPKM 7.7), stomach (RPKM 7.1) and 21 other tissues.

Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

TSPAN15 Products (2)

mRNA Protein Name
NM_001351263.2 NP_001338192.1 tetraspanin-15 isoform 2
NM_012339.5 NP_036471.1 tetraspanin-15 isoform 1

TSPAN15 Protein Structure

Tetraspannin

Tetraspannin: Tetraspanin family (20 - 255)

  • 0
  • 100
  • 200
  • 294 a.a.
Protein Preferred Names Protein Names

tetraspanin-15

  • tetraspan NET-7

TSPAN15 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TSPAN15 O95858 STRIT1 Homo sapiens P0DN84
Validated Y2H
32296183
Intra
TSPAN15 O95858 ADAM10 Homo sapiens O14672
Anti Bait CoIP
26686862
Intra
TSPAN15 O95858 ADAM10 Homo sapiens O14672
Anti Tag CoIP
26686862
Intra
TSPAN15 O95858 ADAM10 Homo sapiens O14672
Anti Tag CoIP
33961781
Intra
TSPAN15 O95858 GYPC Homo sapiens P04921
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Femoral Vein Thrombophlebitis

  • Phlebitis And Thrombophlebitis Of Femoral Vein

  • Thrombophlebitis Of The Femoral Vein

  • Thrombophlebitis Of Deep Femoral Vein
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15163 TSPAN15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TSPAN15 VGNC VGNC:36430
Felis catus TSPAN15 VGNC VGNC:66627
Rattus norvegicus TSPAN15 RGD RGD:1588304
Canis familiaris TSPAN15 VGNC VGNC:47915
Mus musculus TSPAN15 MGD MGI:1917673
Macaca mulatta TSPAN15 VGNC VGNC:79385
Others TSPAN15 NCBI