2. Gene
  3. CALHM1 - calcium homeostasis modulator 1 Gene

CALHM1 - calcium homeostasis modulator 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FAM26C

Gene ID: 255022 | Gene type: protein coding

About CALHM1

Cytogenetic location: 10q24.33 Genomic coordinates (GRCh38): 10:103,453,240-103,458,900 (from NCBI)

This gene has 1 transcript (splice variant), 217 orthologues and 5 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a Calcium Channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010]

CALHM1 Products(1)

mRNA Protein Name
NM_001001412.4 NP_001001412.3 calcium homeostasis modulator protein 1

CALHM1 Protein Structure

Ca_hom_mod

Ca_hom_mod: Calcium homeostasis modulator (2 - 256)

  • 0
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  • 346 a.a.
Protein Preferred Names Protein Names

calcium homeostasis modulator protein 1

family with sequence similarity 26, member C

Related Diseases

Diseases Alias
Alzheimer'S Disease 1

Alzheimer Disease Type 1

Alzheimer'S Disease 1, Early Onset
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-117073 ITH12575 Inhibitor 99.14% Unkown
HY-RS01837 CALHM1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CALHM1 VGNC VGNC:26707
Felis catus CALHM1 VGNC VGNC:60323
Macaca mulatta CALHM1 VGNC VGNC:70615
Mus musculus CALHM1 MGD MGI:3643383
Canis familiaris CALHM1 VGNC VGNC:38667
Rattus norvegicus CALHM1 RGD RGD:1564891