CCDC28A - coiled-coil domain containing 28A Gene

Also Known as LTAP2A; C6orf80; CCRL1AP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25901

Summary

This gene encodes a coiled-coil domain containing protein. Although the specific function of this gene has not yet been determined, this gene is a known translocation partner of nucleoporin 98 in acute leukemias. The resulting fusion gene produces a nucleoporin 98-coiled-coil domain-containing protein 28A chimeric protein which may be involved in promoting myeloproliferative neoplasms. [provided by RefSeq, Jan 2017]
Ubiquitous expression in thyroid (RPKM 10.4), adrenal (RPKM 9.2) and 25 other tissues.

CCDC28A Products (2)

mRNA Protein Name
NM_001379071.1 NP_001366000.1 coiled-coil domain-containing protein 28A isoform 2
NM_015439.3 NP_056254.2 coiled-coil domain-containing protein 28A isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC28A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC28A Q8IWP9 KRTAP9-2 Homo sapiens Q9BYQ4
Validated Y2H
25416956
Intra
CCDC28A Q8IWP9 ICA1 Homo sapiens Q05084
Y2H Prey Pooling
25416956
Intra
CCDC28A Q8IWP9 ICA1 Homo sapiens Q05084
Validated Y2H
25416956
Intra
CCDC28A Q8IWP9 ICA1 Homo sapiens Q05084
Y2H Array
25416956
Intra
CCDC28A Q8IWP9 KIFC3 Homo sapiens Q9BVG8
Y2H Prey Pooling
25416956
Intra
CCDC28A Q8IWP9 KIFC3 Homo sapiens Q9BVG8
Validated Y2H
25416956
Intra
CCDC28A Q8IWP9 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
25416956
Intra
CCDC28A Q8IWP9 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
25416956
Intra
CCDC28A Q8IWP9 MYOG Homo sapiens P15173
Validated Y2H
25416956
Intra
CCDC28A Q8IWP9 MYOG Homo sapiens P15173
Y2H Array
25416956
Intra
CCDC28A Q8IWP9 MYOG Homo sapiens P15173
Y2H Array
31515488
Intra
CCDC28A Q8IWP9 MYOG Homo sapiens P15173
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02061 CCDC88A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21994 Ccdc88a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28511 Ccdc88a Rat Pre-designed siRNA Set A / Unkown