TSLIG3A - tRNA splicing ligase complex subunit 3A Gene
Also Known as FAM98A
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 25940
Summary
Enables protein methyltransferase activity. Involved in positive regulation of cell population proliferation; positive regulation of gene expression; and protein methylation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of tRNA-splicing Ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
Broad expression in testis (RPKM 38.2), brain (RPKM 16.8) and 24 other tissues.
TSLIG3A Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001304538.2 | NP_001291467.1 | protein FAM98A isoform 2 |
| NM_015475.5 | NP_056290.3 | protein FAM98A isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
24608264 | GOA |
| enables protein methyltransferase activity |
IMP
IMP: Inferred from mutant phenotype
|
28040436 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in positive regulation of cell population proliferation |
IMP
IMP: Inferred from mutant phenotype
|
28040436 | GOA |
| involved in positive regulation of gene expression |
IMP
IMP: Inferred from mutant phenotype
|
28040436 | GOA |
| involved in protein methylation |
IMP
IMP: Inferred from mutant phenotype
|
28040436 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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TSLIG3A Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
FAM98A | Q8NCA5 | RTRAF | Homo sapiens | Q9Y224 | 25416956 | |
|
Intra
|
FAM98A | Q8NCA5 | RTRAF | Homo sapiens | Q9Y224 | 25416956 | |
|
Intra
|
FAM98A | Q8NCA5 | RTRAF | Homo sapiens | Q9Y224 | 28040436 | |
|
Intra
|
FAM98A | Q8NCA5 | DDX1 | Homo sapiens | Q92499 | 28040436 | |
|
Intra
|
FAM98A | Q8NCA5 | DDX1 | Homo sapiens | Q92499 | 33961781 | |
|
Intra
|
FAM98A | Q8NCA5 | DDX1 | Homo sapiens | Q92499 | 29992460 |
Cross: Cross-species interaction
Intra: Intraspecies interaction