CHORDC1 - cysteine and histidine rich domain containing 1 Gene

Also Known as CHP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26973

Summary

Enables HSP90 protein binding activity. Predicted to be involved in several processes, including centrosome duplication; obsolete negative regulation of Rho-dependent protein serine/threonine kinase activity; and regulation of cellular response to heat. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in lymph node (RPKM 9.0), appendix (RPKM 8.2) and 25 other tissues.

CHORDC1 Products (2)

mRNA Protein Name
NM_001144073.2 NP_001137545.1 cysteine and histidine-rich domain-containing protein 1 isoform b
NM_012124.3 NP_036256.2 cysteine and histidine-rich domain-containing protein 1 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables Hsp90 protein binding IPI
IPI: Inferred from physical interaction
19875381 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
19875381 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CHORDC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CHORDC1 Q9UHD1 HSP90AA1 Homo sapiens P07900
Pull Down
19875381
Intra
CHORDC1 Q9UHD1 HSP90AA1 Homo sapiens P07900
Y2H Fragment Pooling
23414517
Intra
CHORDC1 Q9UHD1 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
26496610
Intra
CHORDC1 Q9UHD1 HSP90AB1 Homo sapiens P08238
Y2H Fragment Pooling
23414517
Intra
CHORDC1 Q9UHD1 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
25036637
Cross: Cross-species interaction Intra: Intraspecies interaction