PGAP2 - post-GPI attachment to proteins 2 Gene

Also Known as FRAG1; MRT17; MRT21; HPMRS3; CWH43-N

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 27315

Summary

The protein encoded by this gene plays a role in the maturation of glycosylphosphatidylinositol (GPI) anchors on GPI-anchored proteins. Mutations in this gene are associated with an autosomal recessive syndrome characterized by hyperphosphatasia and intellectual disability. [provided by RefSeq, Jul 2017]

PGAP2 Products (1)

mRNA Protein Name
XM_054368456.1 XP_054224431.1 post-GPI attachment to proteins factor 2 isoform X19

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in GPI anchor biosynthetic process IMP
IMP: Inferred from mutant phenotype
29374258 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

post-GPI attachment to proteins factor 2

  • FGF receptor activating protein 1

  • cell wall biogenesis 43 N-terminal homolog

PGAP2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PGAP2 Q9UHJ9 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
25416956
Intra
PGAP2 Q9UHJ9 KRTAP10-9 Homo sapiens P60411
Validated Y2H
25416956
Intra
PGAP2 Q9UHJ9 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
26871637
Intra
PGAP2 Q9UHJ9 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
26871637
Intra
PGAP2 Q9UHJ9 CREB3L1 Homo sapiens Q96BA8
Y2H Array
26871637
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-113041 Prostaglandin A2 99.9% Unkown

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-118728 Prostaglandin A2 methyl ester Control / Unkown
HY-137270 16,16-Dimethyl PGA2 / Unkown
HY-RS00438 AGAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10375 PGAM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10377 PGAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10378 PGAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-165073 15(R)-15-Methyl prostaglandin A2 / Unkown
HY-165074 17-Phenyl trinor-13,14-dihydro prostaglandin A2 / Unkown
HY-165076 19(R)-Hydroxy prostaglandin A2 / Unkown
HY-165088 15(S)-Acetate prostaglandin A2 methyl ester / Unkown
HY-RS21018 Pgam2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21019 Pgap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27535 Pgam2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27536 Pgap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown