2. Gene
  3. IFNL1 - interferon lambda 1 Gene

IFNL1 - interferon lambda 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IL29; IL-29

Gene ID: 282618 | Gene type: protein coding

About IFNL1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,296,407-39,298,673 (from NCBI)

This gene has 1 transcript (splice variant), 140 orthologues and 2 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral Infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]

IFNL1 Products(1)

mRNA Protein Name
NM_172140.2 NP_742152.1 interferon lambda-1 precursor

IFNL1 Protein Structure

IL28A

IL28A: Interleukin-28A (29 - 187)

  • 0
  • 100
  • 200 a.a.
Protein Preferred Names Protein Names

interferon lambda-1

IFN-lambda-1

Recombinant IFNL1 Proteins

Cat. No. Product Name Accession Purity
HY-P7026 IFN-lambda 1/IL-29 Protein, Human Q8IU54 (G20-T200) ≥95%
HY-P72551 IFN-lambda 1/IL-29 Protein, Human (181a.a, HEK293, His) Q8IU54 (G20-T200) ≥95%
HY-P73202 IFN-lambda 1/IL-29 Protein, Human (HEK293) Q8IU54 (M1-T200) ≥95%
HY-P73203 IFN-lambda 1/IL-29 Protein, Human (200a.a, HEK293, His) Q8IU54 (M1-T200) ≥95%
HY-P700121AF Animal-Free IFN-lambda 1/IL-29 Protein, Human (His) Q8IU54 (P23-T200) ≥95%

Related Diseases

Diseases Alias
Psoriasis 12

PSORS12

Psoriasis Susceptibility 12

Psoriasis 12, Susceptibility To
Viral Infectious Disease

Viral Disease

Arbovirus Infections

Virus Infection

Virus Diseases

Viral Infection

Viral Infections

Virus Infections
Inflammatory Bowel Disease 23

IBD23
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99861 Peginterferon lambda-1a / Phase 3
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06591 IFNL1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IFNL1 RGD RGD:6493686
Others IFNL1 NCBI