MCTS1 - MCTS1 re-initiation and release factor Gene

Homo sapiens

Also known as MCT1; MCT-1

Gene ID: 28985 | Gene type: protein coding

About MCTS1

Cytogenetic location: Xq24 Genomic coordinates (GRCh38): X:120,604,101-120,621,159 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 206 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 3.6), brain (RPKM 3.4) and 25 other tissues.

Summary

Predicted to enable translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of translation preinitiation complex; and ribosome disassembly. Located in cytosol and plasma membrane. Colocalizes with cytosolic small ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]

MCTS1 Products(2)

mRNA	Protein	Name
NM_001137554.2	NP_001131026.1	malignant T-cell-amplified sequence 1 isoform 2
NM_014060.3	NP_054779.1	malignant T-cell-amplified sequence 1 isoform 1

MCTS1 Protein Structure

PUA

0
100
181 a.a.

Protein Preferred Names

Protein Names

malignant T-cell-amplified sequence 1

malignant T-cell amplified sequence 1

Related Diseases

Diseases

Alias

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-12750	AZD3965	Inhibitor	99.95%	Phase 1

Pre-clinical Phase

Bioactive Molecules (11)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13248	AR-C155858	Inhibitor	99.62%	Unkown
HY-N4115	Syrosingopine	Inhibitor	99.30%	Unkown
HY-139665	VB124	Inhibitor	99.86%	Unkown
HY-122312	BAY-8002	Inhibitor	98.39%	Unkown
HY-D0067	7ACC1	Inhibitor	99.96%	Unkown
HY-138559	GW604714X	Inhibitor	98.99%	Unkown
HY-18974	MCT1-IN-2		99.16%	Unkown
HY-119996A	AR-C141990 hydrochloride	Inhibitor	≥98.0%	Unkown
HY-119996	AR-C141990		/	Unkown
HY-148574	MCT1-IN-3	Inhibitor	/	Unkown
HY-RS08251	MCTS1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MCTS1	VGNC	VGNC:54172
Rattus norvegicus	MCTS1	RGD	RGD:1566390
Mus musculus	MCTS1	MGD	MGI:1916245
Macaca mulatta	MCTS1	VGNC	VGNC:74558
Bos taurus	MCTS1	VGNC	VGNC:56930

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