CFAP20 - cilia and flagella associated protein 20 Gene
Also Known as GTL3; BUG22; EVORF; RP107; fSAP23; C16orf80
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 29105
Summary
Enables RNA binding activity. Involved in several processes, including positive regulation of feeding behavior; protein polyglutamylation; and regulation of cilium beat frequency involved in ciliary motility. Located in microtubule Cytoskeleton and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in testis (RPKM 19.9), placenta (RPKM 16.9) and 25 other tissues.
CFAP20 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_013242.3 | NP_037374.1 | cilia- and flagella-associated protein 20 |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
24947832 | GOA |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| involved in cilium assembly |
IMP
IMP: Inferred from mutant phenotype
|
24414207 | GOA |
| involved in positive regulation of cell motility |
IDA
IDA: Inferred from direct assay
|
20118210 | GOA |
| involved in positive regulation of feeding behavior |
IDA
IDA: Inferred from direct assay
|
20118210 | GOA |
| involved in protein polyglutamylation |
IMP
IMP: Inferred from mutant phenotype
|
24414207 | GOA |
| involved in regulation of cilium beat frequency involved in ciliary motility |
IDA
IDA: Inferred from direct assay
|
20118210 | GOA |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in axonemal microtubule |
IDA
IDA: Inferred from direct assay
|
36191189 | GOA |
| located in centriole |
IDA
IDA: Inferred from direct assay
|
20118210 | GOA |
| located in ciliary basal body |
IDA
IDA: Inferred from direct assay
|
20118210 | GOA |
| located in cilium |
IDA
IDA: Inferred from direct assay
|
20118210 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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CFAP20 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
CFAP20 | Q9Y6A4 | SFSWAP | Homo sapiens | Q12872 | 33961781 | |
|
Intra
|
CFAP20 | Q9Y6A4 | SFSWAP | Homo sapiens | Q12872 | 28514442 | |
|
Intra
|
CFAP20 | Q9Y6A4 | ARL2BP | Homo sapiens | Q9Y2Y0 | 32296183 | |
|
Intra
|
CFAP20 | Q9Y6A4 | ARL2BP | Homo sapiens | Q9Y2Y0 | 27173435 | |
|
Intra
|
CFAP20 | Q9Y6A4 | ARL2BP | Homo sapiens | Q9Y2Y0 | 32296183 | |
|
Intra
|
CFAP20 | Q9Y6A4 | LRRK2 | Homo sapiens | Q5S007 | 24947832 | |
|
Intra
|
CFAP20 | Q9Y6A4 | CLASRP | Homo sapiens | Q8N2M8 | 33961781 | |
|
Intra
|
CFAP20 | Q9Y6A4 | CLASRP | Homo sapiens | Q8N2M8 | 27173435 | |
|
Intra
|
CFAP20 | Q9Y6A4 | CLASRP | Homo sapiens | Q8N2M8 | 32296183 | |
|
Intra
|
CFAP20 | Q9Y6A4 | CLASRP | Homo sapiens | Q8N2M8 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction