2. Gene
  3. Snca - synuclein alpha Gene

Snca - synuclein alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29219 | Gene type: protein coding

About Snca

Primary_assembly 4: 89,696,420-89,796,262 reverse strand.mRatBN7.2:CM026977.1

This gene has 4 transcripts (splice variants), 189 orthologues, 2 paralogues and is associated with 35 phenotypes. Biased expression in Brain (RPKM 542.3), Spleen (RPKM 92.9) and 1 other tissue.

Summary

Enables several functions, including Phospholipase binding activity; protein N-terminus binding activity; and tubulin binding activity. Involved in several processes, including behavioral response to cocaine; negative regulation of nitrogen compound metabolic process; and response to desipramine. Located in several cellular components, including cytoplasmic vesicle; distal axon; and mitochondrion. Used to study Parkinson's disease and amphetamine abuse. Biomarker of mental depression and neurilemmoma. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; Parkinson's disease 1; and Parkinson's disease 4. Orthologous to human SNCA (synuclein alpha). [provided by Alliance of Genome Resources, Apr 2022]

Snca Products(1)

mRNA Protein Name
NM_019169.3 NP_062042.1 alpha-synuclein

Snca Protein Structure

Synuclein

Synuclein: pfam01387 (0 - 102)

  • 0
  • 100
  • 149 a.a.
Protein Preferred Names Protein Names

alpha-synuclein

synuclein, alpha (non A4 component of amyloid precursor)

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135902A Synucleozid hydrochloride Inhibitor 98.23% Unkown
HY-135902 Synucleozid Inhibitor / Unkown
HY-RS13482 SNCA Human Pre-designed siRNA Set A / Unkown
HY-RS13483 Snca Mouse Pre-designed siRNA Set A / Unkown
HY-RS13484 Snca Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snca NCBI NCBI:6622
Mus musculus Snca NCBI NCBI:20617