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Movronersen sodium

(Synonyms: BIIB-101 sodium; ION-464 sodium)

Movronersen sodium (BIIB-101 sodium; ION-464 sodium) is an antisense oligonucleotide that targets SNCA; it promotes the degradation of SNCA mRNA and downregulates the synthesis of α-synuclein. By reducing the production of α-synuclein, Movronersen sodium decreases protein misfolding and aggregation, thereby interfering with the pathological progression of synucleinopathies. Movronersen sodium is used in research related to multiple system atrophy and associated disorders.

For research use only. We do not sell to patients.

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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Movronersen sodium Chemical Structure
    Movronersen sodium Chemical Structure
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All α-synuclein Isoforms

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All DNA/RNA Synthesis Isoforms

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  • Movronersen sodium Chemical Structure
    Movronersen sodium Chemical Structure DNA, d([2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]rA-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-T-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rC), sodium salt
    1/16
  • DNA, d([2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]rA-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-T-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rC), sodium salt