2. Gene
  3. ST8SIA5 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Gene

ST8SIA5 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SIAT8E; SIAT8-E; ST8SiaV

Gene ID: 29906 | Gene type: protein coding

About ST8SIA5

Cytogenetic location: 18q21.1 Genomic coordinates (GRCh38): 18:46,667,821-46,757,053 (from NCBI)

This gene has 9 transcripts (splice variants), 197 orthologues and 5 paralogues. Biased expression in adrenal (RPKM 3.3), brain (RPKM 3.3) and 3 other tissues.

Summary

The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively. [provided by RefSeq, Jul 2008]

ST8SIA5 Products(3)

mRNA Protein Name
NM_001307986.2 NP_001294915.1 alpha-2,8-sialyltransferase 8E isoform 1
NM_001307987.2 NP_001294916.1 alpha-2,8-sialyltransferase 8E isoform 3
NM_013305.6 NP_037437.2 alpha-2,8-sialyltransferase 8E isoform 2

ST8SIA5 Protein Structure

Glyco_transf_29

Glyco_transf_29: Glycosyltransferase family 29 (sialyltransferase) (115 - 371)

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  • 376 a.a.
Protein Preferred Names Protein Names

alpha-2,8-sialyltransferase 8E

ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13859 ST8SIA5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ST8SIA5 VGNC VGNC:77942
Felis catus ST8SIA5 VGNC VGNC:65738
Canis familiaris ST8SIA5 VGNC VGNC:46867
Mus musculus ST8SIA5 MGD MGI:109243
Rattus norvegicus ST8SIA5 RGD RGD:1302934
Bos taurus ST8SIA5 VGNC VGNC:54494