Amn - amnion associated transmembrane protein Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 314459

Summary

Predicted to enable signaling receptor binding activity. Predicted to be involved in Golgi to plasma membrane protein transport; cobalamin transport; and receptor-mediated endocytosis. Predicted to act upstream of or within excretion. Located in brush border membrane and endocytic vesicle. Part of protein-containing complex. Human ortholog(s) of this gene implicated in megaloblastic anemia. Orthologous to human AMN (amnion associated transmembrane protein). [provided by Alliance of Genome Resources, Apr 2022]

Amn Products (1)

mRNA Protein Name
NM_001108061.1 NP_001101531.1 protein amnionless precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in brush border membrane IDA
IDA: Inferred from direct assay
17990981 RGD
located in endocytic vesicle IDA
IDA: Inferred from direct assay
24122887 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
17990981 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein amnionless

  • amnionless homolog

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10159 Nilotinib 99.94% Yes
HY-10159A Nilotinib monohydrochloride monohydrate 99.91% Yes
HY-10159B Nilotinib hydrochloride 99.17% Yes

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103565 AMN082 Agonist 99.73% Unkown
HY-10159S Nilotinib-d6 99.95% Unkown
HY-10159C Nilotinib hydrochloride dihydrate 99.89% Unkown
HY-RS00068 ABCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-103565A AMN082 free base Agonist 98.37% Unkown
HY-10159S1 Nilotinib-13C,d3 / Unkown
HY-RS00661 AMN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00662 AMN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-134360A ATP-1-Aminonaphthalene-5-sulfonate sodium / Unkown
HY-137604A (γ-AmNS)UTP trisodium / Unkown
HY-137678A GTP-γ-AmNS trisodium / Unkown
HY-168917 9-Aminominocycline Inhibitor / Unkown
HY-RS17996 Traf3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18731 Amn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25218 Amn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amn NCBI NCBI:81693