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  3. HOXC11 - homeobox C11 Gene

HOXC11 - homeobox C11 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HOX3H

Gene ID: 3227 | Gene type: protein coding

About HOXC11

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:53,973,126-53,977,643 (from NCBI)

This gene has 2 transcripts (splice variants), 204 orthologues, 42 paralogues and is associated with 41 phenotypes. Low expression observed in reference dataset.

Summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]

HOXC11 Products(1)

mRNA Protein Name
NM_014212.4 NP_055027.1 homeobox protein Hox-C11

HOXC11 Protein Structure

DUF3528

DUF3528: Protein of unknown function (DUF3528) (42 - 178)

Homeobox

Homeobox: Homeobox domain (233 - 289)

  • 0
  • 100
  • 200
  • 304 a.a.
Protein Preferred Names Protein Names

homeobox protein Hox-C11

homeo box C11

Related Diseases

Diseases Alias
Ectodermal Dysplasia 4, Hair/Nail Type

Pure Hair And Nail Ectodermal Dysplasia

ECTD4

Ectodermal Dysplasia, Pure Hair-Nail Type

Ectodermal Dysplasia, 'Pure' Hair/Nail Type

Hned

Hair-Nail Ectodermal Dysplasia

Phned

Ectodermal Dysplasia Pure Hair-Nail Type

Ectodermal Dysplasia, 'Pure' Hair-Nail Type

Dysplasia, Ectodermal, Type 4, Hair/Nail
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06315 HOXC11 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HOXC11 RGD RGD:6489991
Canis familiaris HOXC11 VGNC VGNC:57427
Macaca mulatta HOXC11 VGNC VGNC:99942
Felis catus HOXC11 VGNC VGNC:84030
Bos taurus HOXC11 VGNC VGNC:56207
Mus musculus HOXC11 MGD MGI:96193