Bpi - bactericidal permeablility increasing protein Gene

Also Known as Bpifd1; 9230105K17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 329547

Summary

Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in several processes, including negative regulation of cytokine production; negative regulation of macrophage activation; and response to bacterium. Located in cytoplasm. Human ortholog(s) of this gene implicated in Crohn's disease. Orthologous to human BPI (bactericidal permeability increasing protein). [provided by Alliance of Genome Resources, Apr 2022]

Bpi Products (2)

mRNA Protein Name
NM_001356542.1 NP_001343471.1 bactericidal permeability-increasing protein isoform 2 precursor
NM_177850.3 NP_808518.1 bactericidal permeability-increasing protein isoform 1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15590754 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bactericidal permeability-increasing protein

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. 상품명 효과
Purity Rare Diseases
HY-15164A Icotinib Inhibitor 99.96% Yes
HY-15164 Icotinib Hydrochloride Inhibitor 99.89% Yes

Clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명 효과
Purity Phase
HY-109189A Rezivertinib hydrochloride Inhibitor / Phase 3
HY-114356 BPI-9016M Inhibitor 97.13% Phase 1
HY-164464 BPI-15086 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-109189 Rezivertinib Inhibitor 99.62% Unkown
HY-141703A DC-BPi-11 hydrochloride Inhibitor 97.36% Unkown
HY-150211 DC-BPi-03 Inhibitor 99.77% Unkown
HY-156646 Tibremciclib Inhibitor / Unkown
HY-141703 DC-BPi-11 Inhibitor / Unkown
HY-15164AS Icotinib-d4 / Unkown
HY-173165 OA-Br-1 / Unkown
HY-178697 DC-BPi-07 Inhibitor / Unkown
HY-RS01580 BPI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18324 Bpi Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24802 Bpi Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bpi NCBI NCBI:671