Bmx - BMX non-receptor tyrosine kinase Gene

Rattus norvegicus

Also known as RGD1565643

Gene ID: 367786 | Gene type: protein coding

About Bmx

Primary_assembly X: 30,227,251-30,289,993 forward strand.mRatBN7.2:CM026994.1

This gene has 1 transcript (splice variant), 137 orthologues, 32 paralogues and is associated with 3 phenotypes. Biased expression in Lung (RPKM 13.7), Heart (RPKM 9.) and 9 other tissues.

Summary

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in B cell receptor signaling pathway; adaptive immune response; and peptidyl-tyrosine autophosphorylation. Predicted to be located in nucleoplasm and ruffle membrane. Orthologous to human BMX (BMX non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Bmx Products(1)

mRNA	Protein	Name
NM_001109016.1	NP_001102486.1	cytoplasmic tyrosine-protein kinase BMX

Bmx Protein Structure

PH_Btk

SH2_Tec_Bmx

PKc_like

0
200
400
600
655 a.a.

Protein Preferred Names

Protein Names

cytoplasmic tyrosine-protein kinase BMX

Related Agents

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-130574	MnTE-2-PyP chloride		≥95.0%	Phase 2
HY-111553	TAS0728	Inhibitor	99.15%	Phase 1

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-80002	BMX-IN-1	Inhibitor	99.84%	Unkown
HY-101267	CHMFL-BMX-078	Inhibitor	≥98.0%	Unkown
HY-117900	PF-06250112	Inhibitor	/	Unkown
HY-145373	BMS-986143	Inhibitor	/	Unkown
HY-117900A	(Rac)-PF-06250112		/	Unkown
HY-148585	BTK-IN-22	Inhibitor	/	Unkown
HY-148594	BTK-IN-23	Inhibitor	/	Unkown
HY-RS01557	BMX Human Pre-designed siRNA Set A		/	Unkown
HY-RS01558	Bmx Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS01559	Bmx Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bmx	NCBI	NCBI:660

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