BTK-IN-23
BTK-IN-23 is a BTK inhibitor (IC50: 12.8 nM). BTK-IN-23 also inhibits BLX and BMX with IC50s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997).
For research use only. We do not sell to patients.
- CAS No.: 2573048-11-8
- Formula: C27H28N6O2
- Molecular Weight:468.55
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
BTK-IN-23 (Compound 3) inhibits BTK autophosphorylation in Jeko-1 cells, with an IC50 of 314 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Jeko-1 cell
-
Concentration:0.01, 0.1, 1, 10 μM
-
Incubation Time:2 h
-
Result:Inhibited BTK autophosphorylation.
Chemical Information
-
CAS No. 2573048-11-8
-
Molecular Weight 468.55
-
Formula C27H28N6O2
-
SMILES
C=CC(N1CCC[C@H](C1)N2N=C(C3=C(N=CN=C32)N)C4=C(C)C=C(C=C4C)OC5=CC=CC=C5)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BTK-IN-23 Related Classifications
HY-148594 Related Classifications
Powered by Bioz