BTK-IN-23
BTK-IN-23 is a BTK inhibitor (IC50: 12.8 nM). BTK-IN-23 also inhibits BLX and BMX with IC50s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997).
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- No. CAS: 2573048-11-8
- Fòrmula: C27H28N6O2
- Peso molecular:468.55
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
BTK-IN-23 (Compound 3) inhibits BTK autophosphorylation in Jeko-1 cells, with an IC50 of 314 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Jeko-1 cell
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Concentration:0.01, 0.1, 1, 10 μM
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Incubation Time:2 h
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Result:Inhibited BTK autophosphorylation.
Chemical Information
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No. CAS 2573048-11-8
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Peso molecular 468.55
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Fòrmula C27H28N6O2
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SMILES
C=CC(N1CCC[C@H](C1)N2N=C(C3=C(N=CN=C32)N)C4=C(C)C=C(C=C4C)OC5=CC=CC=C5)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BTK-IN-23 Related Classifications
HY-148594 Related Classifications
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