DENND10 - DENN domain containing 10 Gene

Also Known as FAM45A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 404636

Summary

Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endosome transport via multivesicular body sorting pathway; protein transport; and regulation of early endosome to late endosome transport. Located in late endosome. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 10.5), esophagus (RPKM 8.9) and 25 other tissues.

DENND10 Products (4)

mRNA Protein Name
NM_001303111.2 NP_001290040.1 DENN domain-containing protein 10 isoform 2
NM_001303112.2 NP_001290041.1 DENN domain-containing protein 10 isoform 3
NM_001303113.2 NP_001290042.1 DENN domain-containing protein 10 isoform 4
NM_207009.4 NP_996892.1 DENN domain-containing protein 10 isoform 1

DENND10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
DENND10 Q8TCE6 CCDC93 Homo sapiens Q567U6 33961781
Intra
DENND10 Q8TCE6 CCDC93 Homo sapiens Q567U6 37172566
Cross: Cross-species interaction Intra: Intraspecies interaction