DENND10 - DENN domain containing 10 Gene
Also Known as FAM45A
Species: Homo sapiens
Summary
Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endosome transport via multivesicular body sorting pathway; protein transport; and regulation of early endosome to late endosome transport. Located in late endosome. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 10.5), esophagus (RPKM 8.9) and 25 other tissues.
DENND10 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001303111.2 | NP_001290040.1 | DENN domain-containing protein 10 isoform 2 |
| NM_001303112.2 | NP_001290041.1 | DENN domain-containing protein 10 isoform 3 |
| NM_001303113.2 | NP_001290042.1 | DENN domain-containing protein 10 isoform 4 |
| NM_207009.4 | NP_996892.1 | DENN domain-containing protein 10 isoform 1 |
DENND10 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Références |
|---|---|---|---|---|---|---|---|
|
Intra
|
DENND10 | Q8TCE6 | CCDC93 | Homo sapiens | Q567U6 | 33961781 | |
|
Intra
|
DENND10 | Q8TCE6 | CCDC93 | Homo sapiens | Q567U6 | 37172566 |