Dnmt3a - DNA methyltransferase 3 alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 444984

Summary

Enables chromatin binding activity. Involved in several processes, including cellular response to ethanol; hepatocyte apoptotic process; and response to vitamin A. Located in cytoplasm and nucleus. Used to study lung carcinoma and middle cerebral artery infarction. Biomarker of congenital heart disease; hepatocellular carcinoma; and prostatitis. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia; acute lymphoblastic leukemia; acute myeloid leukemia; myelodysplastic syndrome; and stomach Cancer. Orthologous to human DNMT3A (DNA Methyltransferase 3 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Dnmt3a Products (2)

mRNA Protein Name
NM_001003957.1 NP_001003957.1 DNA (cytosine-5)-methyltransferase 3A isoform 2
NM_001003958.1 NP_001003958.1 DNA (cytosine-5)-methyltransferase 3A isoform 1
Protein Preferred Names Protein Names

DNA (cytosine-5)-methyltransferase 3A

  • DNA (cytosine-5-)-methyltransferase 3 alpha

  • DNA methyltransferase 3A

  • cysteine methyltransferase DNMT3A

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B2194 γ-Oryzanol Inhibitor 99.66% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-176230 DNMT-IN-5 Inhibitor / Phase 3

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13962 SGI-1027 99.79% Unkown
HY-151136 DY-46-2 Inhibitor 99.86% Unkown
HY-101925 CM-272 98.0% Unkown
HY-144433 DNMT3A-IN-1 Inhibitor 99.94% Unkown
HY-124131 DS-437 Inhibitor 99.22% Unkown
HY-RS03911 DNMT3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-111544 EML741 Inhibitor / Unkown
HY-179409 MC3817 / Unkown
HY-13689G Go 6983 (GMP) / Unkown
HY-150025 (4aS,8aR)-NPD-001 / Unkown
HY-172217 DNMT1-IN-5 / Unkown
HY-179409A MC3817 free base / Unkown
HY-181690 Menin-MLL-IN-37 Inhibitor / Unkown
HY-181955 MS1129 / Unkown
HY-182009 DNMT-IN-6 / Unkown
HY-182956 DNMT1 Degrader-1 Degrader / Unkown
HY-184332 DNMT3A-IN-4 Inhibitor / Unkown
HY-RS16763 Dnmt3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23203 Dnmt3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnmt3a NCBI NCBI:1788