TIFAB - TIFA inhibitor Gene

Homo sapiens

Gene ID: 497189 | Gene type: protein coding

About TIFAB

Cytogenetic location: 5q31.1 Genomic coordinates (GRCh38): 5:135,444,226-135,452,351 (from NCBI)

This gene has 1 transcript (splice variant), 73 orthologues and 1 paralogue. Biased expression in lymph node (RPKM 4.5), appendix (RPKM 3.4) and 12 other tissues.

Summary

TIFAB associates with TIFA (MIM 609028) and inhibits TIFA-mediated activation of NF-kappa-B (NFKB1; MIM 164011) (Matsumura et al., 2004 [PubMed 15047173]).[supplied by OMIM, Mar 2009]

TIFAB Products(1)

mRNA	Protein	Name
NM_001099221.2	NP_001092691.1	TRAF-interacting protein with FHA domain-containing protein B

TIFAB Protein Structure

FHA

0
100
161 a.a.

Protein Preferred Names

Protein Names

TRAF-interacting protein with FHA domain-containing protein B

TIFA-like protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14522	TIFAB Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TIFAB	VGNC	VGNC:47367
Mus musculus	TIFAB	MGD	MGI:2385852
Felis catus	TIFAB	VGNC	VGNC:102344
Rattus norvegicus	TIFAB	RGD	RGD:1311681
Macaca mulatta	TIFAB	VGNC	VGNC:79944
Bos taurus	TIFAB	VGNC	VGNC:52889

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