CLDN20 - claudin 20 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 49861

Summary

This gene encodes a member of the Claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. [provided by RefSeq, Jun 2010]
Low expression observed in reference dataset.

CLDN20 Products (1)

mRNA Protein Name
NM_001001346.3 NP_001001346.1 claudin-20 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in tight junction IDA
IDA: Inferred from direct assay
30734065 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLDN20 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
CLDN20 P56880 TMEM239 Homo sapiens Q8WW34-2
Validated Y2H
32296183
Intra
CLDN20 P56880 ANKRD46 Homo sapiens Q86W74-2
Validated Y2H
32296183
Intra
CLDN20 P56880 PLP1 Homo sapiens P60201-2
Validated Y2H
32296183
Intra
CLDN20 P56880 CNIH3 Homo sapiens Q8TBE1
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02763 CLDN10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02770 CLDN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown