EMC9 - ER membrane protein complex subunit 9 Gene

Homo sapiens

Also known as CGI-112; FAM158A; C14orf122

Gene ID: 51016 | Gene type: protein coding

About EMC9

This gene has 7 transcripts (splice variants), 1 gene allele, 187 orthologues and 1 paralogue. Ubiquitous expression in appendix (RPKM 5.4), duodenum (RPKM 4.9) and 25 other tissues.

Summary

Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in cytoplasm. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022]

EMC9 Products(5)

mRNA	Protein	Name
NM_001346874.2	NP_001333803.1	ER membrane protein complex subunit 9 isoform b precursor
NM_001346875.2	NP_001333804.1	ER membrane protein complex subunit 9 isoform b precursor
NM_001346876.2	NP_001333805.1	ER membrane protein complex subunit 9 isoform b precursor
NM_001346877.2	NP_001333806.1	ER membrane protein complex subunit 9 isoform b precursor
NM_016049.4	NP_057133.2	ER membrane protein complex subunit 9 isoform a

EMC9 Protein Structure

UPF0172

0
100
208 a.a.

Protein Preferred Names

Protein Names

ER membrane protein complex subunit 9

UPF0172 protein FAM158A

Related Diseases

Diseases

Alias

Intraocular Retinoblastoma

Pediatric Intraocular Retinoblastoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04343	EMC9 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	EMC9	MGD	MGI:1934682
Felis catus	EMC9	VGNC	VGNC:61838
Bos taurus	EMC9	VGNC	VGNC:28468
Macaca mulatta	EMC9	VGNC	VGNC:72077
Canis familiaris	EMC9	VGNC	VGNC:40338
Rattus norvegicus	EMC9	RGD	RGD:1308113