EMC9 - ER membrane protein complex subunit 9 Gene

Also Known as CGI-112; FAM158A; C14orf122

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51016

About EMC9

This gene has 7 transcripts (splice variants), 1 gene allele, 187 orthologues and 1 paralogue. Ubiquitous expression in appendix (RPKM 5.4), duodenum (RPKM 4.9) and 25 other tissues.

Summary

Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in cytoplasm. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022]

EMC9 Products (5)

mRNA Protein Name
NM_001346874.2 NP_001333803.1 ER membrane protein complex subunit 9 isoform b precursor
NM_001346875.2 NP_001333804.1 ER membrane protein complex subunit 9 isoform b precursor
NM_001346876.2 NP_001333805.1 ER membrane protein complex subunit 9 isoform b precursor
NM_001346877.2 NP_001333806.1 ER membrane protein complex subunit 9 isoform b precursor
NM_016049.4 NP_057133.2 ER membrane protein complex subunit 9 isoform a

EMC9 Protein Structure

UPF0172

UPF0172: Uncharacterised protein family (UPF0172) (1 - 192)

  • 0
  • 100
  • 208 a.a.
Protein Preferred Names Protein Names

ER membrane protein complex subunit 9

  • UPF0172 protein FAM158A

EMC9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Anti Tag CoIP
35271311
Intra
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Anti Tag CoIP
33961781
Intra
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Anti Tag CoIP
28514442
Intra
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Y2H Array
25416956
Intra
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Intraocular Retinoblastoma

  • Pediatric Intraocular Retinoblastoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04343 EMC9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EMC9 MGD MGI:1934682
Felis catus EMC9 VGNC VGNC:61838
Bos taurus EMC9 VGNC VGNC:28468
Macaca mulatta EMC9 VGNC VGNC:72077
Canis familiaris EMC9 VGNC VGNC:40338
Rattus norvegicus EMC9 RGD RGD:1308113
Others EMC9 NCBI