GOLGA7 - golgin A7 Gene

Also Known as GCP16; GOLGA7A; HSPC041; GOLGA3AP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51125

About GOLGA7

Cytogenetic location: 8p11.21 Genomic coordinates (GRCh38): 8:41,490,396-41,510,980 (from NCBI)

This gene has 34 transcripts (splice variants), 289 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 33.3), testis (RPKM 26.7) and 25 other tissues.

Summary

Involved in Golgi to plasma membrane protein transport; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Acts upstream of or within Golgi to plasma membrane transport. Located in Golgi membrane and Golgi stack. Is intrinsic component of Golgi membrane. Part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

GOLGA7 Products (5)

mRNA Protein Name
NM_001002296.2 NP_001002296.1 golgin subfamily A member 7 isoform a
NM_001174124.2 NP_001167595.1 golgin subfamily A member 7 isoform b
NM_001362979.1 NP_001349908.1 golgin subfamily A member 7 isoform a
NM_001362980.2 NP_001349909.1 golgin subfamily A member 7 isoform a
NM_016099.3 NP_057183.2 golgin subfamily A member 7 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14522980 GOA
Biological Process GO Annotation Evidence References Source
involved in Golgi to plasma membrane protein transport IDA
IDA: Inferred from direct assay
14522980 GOA
acts upstream of or within Golgi to plasma membrane transport IDA
IDA: Inferred from direct assay
14522980 GOA
involved in peptidyl-L-cysteine S-palmitoylation IDA
IDA: Inferred from direct assay
16000296 GOA
involved in protein stabilization IDA
IDA: Inferred from direct assay
16000296 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
14522980 GOA
located in Golgi stack IDA
IDA: Inferred from direct assay
14522980 GOA
part of palmitoyltransferase complex IDA
IDA: Inferred from direct assay
16000296 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GOLGA7 Protein Structure

Erf4

Erf4: Golgin subfamily A member 7/ERF4 family (12 - 122)

  • 0
  • 100
  • 137 a.a.
Protein Preferred Names Protein Names

golgin subfamily A member 7

  • Golgi complex-associated protein of 16kDa

GOLGA7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GOLGA7 Q7Z5G4 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
GOLGA7 Q7Z5G4 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
GOLGA7 Q7Z5G4 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
GOLGA7 Q7Z5G4 KCNIP2 Homo sapiens Q9NS61-2
Validated Y2H
32296183
Cross
GOLGA7 Q7Z5G4 S SARS-CoV-2 P0DTC2
Anti Tag CoIP
34117209
Cross
GOLGA7 Q7Z5G4 S SARS-CoV-2 P0DTC2
Confocal
35115020
Intra
GOLGA7 Q7Z5G4 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra
GOLGA7 Q7Z5G4 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra
GOLGA7 Q7Z5G4 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra
GOLGA7 Q7Z5G4 MESD Homo sapiens Q14696
Y2H Array
32296183
Intra
GOLGA7 Q7Z5G4 MESD Homo sapiens Q14696
Y2H Prey Pooling
32296183
Intra
GOLGA7 Q7Z5G4 KCNIP3 Homo sapiens Q9Y2W7
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05588 GOLGA7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05589 GOLGA7B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GOLGA7 MGD MGI:1931029
Canis familiaris GOLGA7 VGNC VGNC:41342
Bos taurus GOLGA7 VGNC VGNC:29487
Rattus norvegicus GOLGA7 RGD RGD:1359725
Macaca mulatta GOLGA7 VGNC VGNC:73002
Others GOLGA7 NCBI