TRIM17 - tripartite motif containing 17 Gene

Also Known as RBCC; terf; RNF16

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51127

Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein is expressed almost exclusively in the testis, but its function is unknown. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Biased expression in testis (RPKM 5.7), spleen (RPKM 1.3) and 11 other tissues.

TRIM17 Products (4)

mRNA Protein Name
NM_001024940.3 NP_001020111.1 E3 ubiquitin-protein ligase TRIM17 isoform 1
NM_001134855.2 NP_001128327.1 E3 ubiquitin-protein ligase TRIM17 isoform 3
NM_001438323.1 NP_001425252.1 E3 ubiquitin-protein ligase TRIM17 isoform 4
NM_016102.4 NP_057186.1 E3 ubiquitin-protein ligase TRIM17 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables protein-macromolecule adaptor activity IPI
IPI: Inferred from physical interaction
25127057 GOA
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
19358823 GOA
Biological Process GO Annotation Evidence References Source
involved in autophagy IDA
IDA: Inferred from direct assay
25127057 GOA
involved in protein autoubiquitination IDA
IDA: Inferred from direct assay
19358823 GOA
involved in regulation of protein localization IMP
IMP: Inferred from mutant phenotype
25127057 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRIM17 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TRIM17 Q9Y577 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
TRIM17 Q9Y577 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
TRIM17 Q9Y577 TRIM39 Homo sapiens Q9HCM9
Y2H Array
25416956
Intra
TRIM17 Q9Y577 TRIM39 Homo sapiens Q9HCM9
Anti Tag CoIP
22493164
Intra
TRIM17 Q9Y577 TRIM39 Homo sapiens Q9HCM9
Y2H Pooling
16189514
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (25)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15024 TRIM16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15032 TRIM27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15019 TRIM10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15020 TRIM11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15021 TRIM13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15022 TRIM14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15023 TRIM15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15041 TRIM37 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15051 TRIM47 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15067 TRIM67 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15069 TRIM7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15070 TRIM71 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19080 Trim16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19824 Trim27 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20197 Trim14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20198 Trim15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21210 Trim47 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21958 Trim13 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22880 Trim7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25571 Trim16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26320 Trim27 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26702 Trim14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27726 Trim47 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28475 Trim13 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29394 Trim7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown