2. Gene
  3. IPO11 - importin 11 Gene

IPO11 - importin 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RanBP11

Gene ID: 51194 | Gene type: protein coding

About IPO11

Cytogenetic location: 5q12.1 Genomic coordinates (GRCh38): 5:62,412,763-62,628,582 (from NCBI)

This gene has 14 transcripts (splice variants), 202 orthologues and 4 paralogues. Ubiquitous expression in testis (RPKM 13.7), thyroid (RPKM 6.7) and 25 other tissues.

Summary

Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied by OMIM, Sep 2008]

IPO11 Products(2)

mRNA Protein Name
NM_001134779.2 NP_001128251.1 importin-11 isoform 1
NM_016338.5 NP_057422.3 importin-11 isoform 2

IPO11 Protein Structure

IBN_N

IBN_N: Importin-beta N-terminal domain (28 - 97)

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  • 975 a.a.
Protein Preferred Names Protein Names

importin-11

Ran binding protein 11

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06866 IPO11 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus IPO11 VGNC VGNC:62953
Canis familiaris IPO11 VGNC VGNC:49760
Bos taurus IPO11 VGNC VGNC:50068
Macaca mulatta IPO11 VGNC VGNC:73633
Mus musculus IPO11 MGD MGI:2442377