GDE1 - glycerophosphodiester phosphodiesterase 1 Gene

Also Known as MIR16; 363E6.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51573

About GDE1

Cytogenetic location: 16p12.3 Genomic coordinates (GRCh38): 16:19,501,693-19,522,098 (from NCBI)

This gene has 5 transcripts (splice variants), 250 orthologues and 5 paralogues. Ubiquitous expression in colon (RPKM 28.1), fat (RPKM 25.8) and 25 other tissues.

Summary

Predicted to enable glycerophosphodiester phosphodiesterase activity; glycerophosphoinositol glycerophosphodiesterase activity; and lysophospholipase activity. Predicted to be involved in N-acylethanolamine metabolic process; ethanolamine metabolic process; and phospholipid metabolic process. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GDE1 Products (3)

mRNA Protein Name
NM_001324066.2 NP_001310995.1 glycerophosphodiester phosphodiesterase 1 isoform 2
NM_001324067.2 NP_001310996.1 glycerophosphodiester phosphodiesterase 1 isoform 3
NM_016641.4 NP_057725.1 glycerophosphodiester phosphodiesterase 1 isoform 1

GDE1 Protein Structure

GDPD

GDPD: Glycerophosphoryl diester phosphodiesterase family (70 - 309)

  • 0
  • 100
  • 200
  • 300
  • 331 a.a.
Protein Preferred Names Protein Names

glycerophosphodiester phosphodiesterase 1

  • RGS16-interacting membrane protein

GDE1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
GDE1 Q9NZC3 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra
GDE1 Q9NZC3 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Serine Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS05348 GDE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W127407 Glycerophospho-N-arachidonoyl ethanolamine / Unkown
HY-RS21346 Gde1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27865 Gde1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GDE1 MGD MGI:1891827
Canis familiaris GDE1 VGNC VGNC:103677
Rattus norvegicus GDE1 RGD RGD:621788
Macaca mulatta GDE1 VGNC VGNC:72807
Felis catus GDE1 VGNC VGNC:62501
Bos taurus GDE1 VGNC VGNC:29298
Others GDE1 NCBI