2. Gene
  3. GINS2 - GINS complex subunit 2 Gene

GINS2 - GINS complex subunit 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PSF2; Pfs2; HSPC037

Gene ID: 51659 | Gene type: protein coding

About GINS2

Cytogenetic location: 16q24.1 Genomic coordinates (GRCh38): 16:85,676,198-85,688,954 (from NCBI)

This gene has 3 transcripts (splice variants) and 208 orthologues. Broad expression in bone marrow (RPKM 11.1), lymph node (RPKM 10.1) and 20 other tissues.

Summary

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]

GINS2 Products(1)

mRNA Protein Name
NM_016095.3 NP_057179.1 DNA replication complex GINS protein PSF2

GINS2 Protein Structure

Sld5

Sld5: GINS complex protein (42 - 153)

  • 0
  • 100
  • 185 a.a.
Protein Preferred Names Protein Names

DNA replication complex GINS protein PSF2

GINS complex subunit 2 (Psf2 homolog)

Related Diseases

Diseases Alias
Colon Small Cell Carcinoma

Colonic Small Cell Carcinoma

Colon Small Cell Neuroendocrine Carcinoma
Meier-Gorlin Syndrome 5

MGORS5

Meier-Gorlin Syndrome, Type 5
Paronychia

Paronychia Inflammation

Onychomycosis

Fungal Nail Infection

Infected Nailfold

Onychia And Paronychia Of Finger

Onychia And Paronychia Of Toe

Fungal Infection Of The Nails
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05431 GINS2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GINS2 VGNC VGNC:99509
Canis familiaris GINS2 VGNC VGNC:41221
Bos taurus GINS2 VGNC VGNC:29361
Felis catus GINS2 VGNC VGNC:62554
Mus musculus GINS2 MGD MGI:1921019
Rattus norvegicus GINS2 RGD RGD:1311055