UBASH3A - ubiquitin associated and SH3 domain containing A Gene

Homo sapiens

Also known as TULA; CLIP4; STS-2; TULA-1

Gene ID: 53347 | Gene type: protein coding

About UBASH3A

Cytogenetic location: 21q22.3 Genomic coordinates (GRCh38): 21:42,403,902-42,447,684 (from NCBI)

This gene has 9 transcripts (splice variants), 132 orthologues and 1 paralogue. Biased expression in lymph node (RPKM 3.3), appendix (RPKM 1.9) and 12 other tissues.

Summary

This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced Apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

UBASH3A Products(3)

mRNA	Protein	Name
NM_001001895.3	NP_001001895.1	ubiquitin-associated and SH3 domain-containing protein A isoform 2
NM_001243467.2	NP_001230396.1	ubiquitin-associated and SH3 domain-containing protein A isoform 3
NM_018961.4	NP_061834.1	ubiquitin-associated and SH3 domain-containing protein A isoform 1

UBASH3A Protein Structure

SH3_9

His_Phos_1

0
200
400
600
661 a.a.

Protein Preferred Names

Protein Names

ubiquitin-associated and SH3 domain-containing protein A

T-cell ubiquitin ligand 1

Recombinant UBASH3A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76687	UBASH3A Protein, Human (His)	P57075-2 (A354-N623)	≥95%

Related Diseases

Diseases

Alias

Celiac Disease 1

Celiac Disease	Coeliac Disease
Celiac Sprue	Celiac Disease, Susceptibility To
Gluten-Sensitive Enteropathy	Nontropical Sprue
Sprue	CELIAC1
Celiac Disease, Susceptibility To, 1	Celiac Sprue 1
Celiac Sprue, Susceptibility To, 1	Gluten-Sensitive Enteropathy 1
Gluten-Sensitive Enteropathy, Susceptibility To, 1	Idiopathic Steatorrhea
Cœliac Disease	Gluten Intolerance
Gluten-Induced Enteropathy	Gluten Enteropathy
Celiac Disease, Susceptibility To, Type 1	Childhood Celiac Disease
Coeliac Rickets	Gee Disease
Gee-Herter Disease	Heubner-Herter Disease
Idiopathic Steatorrhoea	Thaysen'S Disease
Herter Gee Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15331	UBASH3A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	UBASH3A	VGNC	VGNC:66755
Mus musculus	UBASH3A	MGD	MGI:1926074
Canis familiaris	UBASH3A	VGNC	VGNC:53047
Bos taurus	UBASH3A	VGNC	VGNC:36574
Macaca mulatta	UBASH3A	VGNC	VGNC:78687
Rattus norvegicus	UBASH3A	RGD	RGD:1310305
Others	UBASH3A	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.