LRRK2 - leucine rich repeat kinase 2 Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 535652

About LRRK2

Primary_assembly 5: 40,461,232-40,666,425 reverse strand.ARS-UCD1.2:CM008172.2

This gene has 1 transcript (splice variant), 191 orthologues and 23 paralogues.

LRRK2 Products (1)

mRNA Protein Name
NM_001206086.3 NP_001193015.2 leucine-rich repeat serine/threonine-protein kinase 2

LRRK2 Protein Structure

LRR_RI

LRR_RI: sd00033 (984 - 1011)

LRR

LRR: COG4886 (1011 - 1285)

LRR_RI

LRR_RI: sd00033 (1012 - 1035)

LRR_RI

LRR_RI: sd00033 (1036 - 1058)

LRR_RI

LRR_RI: sd00033 (1059 - 1083)

LRR_RI

LRR_RI: sd00033 (1084 - 1107)

LRR_RI

LRR_RI: sd00033 (1108 - 1129)

LRR_RI

LRR_RI: sd00033 (1130 - 1153)

LRR_RI

LRR_RI: sd00033 (1154 - 1196)

LRR_RI

LRR_RI: sd00033 (1197 - 1220)

LRR_RI

LRR_RI: sd00033 (1221 - 1245)

LRR_RI

LRR_RI: sd00033 (1269 - 1296)

P-loop_NTPase

P-loop_NTPase: cl38936 (1333 - 1506)

COR

COR: cl24610 (1526 - 1739)

STKc_LRRK2

STKc_LRRK2: cd14068 (1883 - 2134)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2400
  • 2527 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat serine/threonine-protein kinase 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-112809 GSK2646264 Inhibitor 99.74% Phase 1

Pre-clinical Phase

Bioactive Molecules (63)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100411 MLi-2 Inhibitor 99.80% Unkown
HY-13687 IKK 16 Inhibitor 99.88% Unkown
HY-10875 LRRK2-IN-1 Inhibitor 99.04% Unkown
HY-148030 XL01126 Inhibitor 98.90% Unkown
HY-40294 Indazole Inhibitor 99.83% Unkown
HY-12477 PF-06447475 Inhibitor 99.94% Unkown
HY-15796 GNE0877 Inhibitor 99.81% Unkown
HY-13237 GSK2578215A Inhibitor 99.82% Unkown
HY-18163 GNE-7915 Inhibitor 99.81% Unkown
HY-13687A IKK 16 hydrochloride Inhibitor 99.95% Unkown
HY-13488 HG-10-102-01 Inhibitor 99.55% Unkown
HY-120085 PFE-360 Inhibitor 99.10% Unkown
HY-P5979 LRRKtide Substrate 99.94% Unkown
HY-15800A CZC-25146 Inhibitor 99.10% Unkown
HY-12282 GNE-9605 Inhibitor 99.51% Unkown
HY-155150 JH-XII-03-02 Degrader 99.33% Unkown
HY-111493 LRRK2 inhibitor 1 Inhibitor 99.80% Unkown
HY-152107 LRRK2-IN-7 Inhibitor 98.03% Unkown
HY-156429 MK-1468 Inhibitor 99.69% Unkown
HY-B0792 CZC-54252 Inhibitor 98.05% Unkown
HY-142647 EB-42486 Inhibitor 99.62% Unkown
HY-163064 CC-3240 Degrader 98.23% Unkown
HY-16936 JH-II-127 Inhibitor 98.0% Unkown
HY-18163A GNE-7915 tosylate Inhibitor 99.06% Unkown
HY-112855 PF-06454589 Inhibitor 99.91% Unkown
HY-174420 RN277 Inhibitor / Unkown
HY-W107722 IN04 98.51% Unkown
HY-148353 PF-06455943 Inhibitor 98.21% Unkown
HY-152107A (R,R)-LRRK2-IN-7 Inhibitor / Unkown
HY-75368 SRI-31255 Inhibitor 99.88% Unkown
HY-174427 RN341 Inhibitor / Unkown
HY-145317 LRRK2-IN-2 Inhibitor / Unkown
HY-162699 LY2023-001 Inhibitor / Unkown
HY-145318 LRRK2-IN-3 Inhibitor / Unkown
HY-158365 LRRK2-IN-14 Inhibitor / Unkown
HY-177016 LRRK2-IN-19 Inhibitor / Unkown
HY-168041 LRRK2-IN-15 Inhibitor / Unkown
HY-171802 PROTAC LRRK2 Degrader-2 Degrader / Unkown
HY-186110 PROTAC LRRK2 Degrader-5 Degrader / Unkown
HY-153058 LRRK2-IN-8 Inhibitor / Unkown
HY-151444 LRRK2-IN-6 Inhibitor / Unkown
HY-169576 LRRK2-IN-16 Inhibitor / Unkown
HY-184198 LRRK2-IN-22 Inhibitor / Unkown
HY-178796 PROTAC LRRK2 Degrader-4 Degrader / Unkown
HY-182928 LRRK2-IN-21 Inhibitor / Unkown
HY-B0792A CZC-54252 hydrochloride Inhibitor 98.44% Unkown
HY-171801 PROTAC LRRK2 Degrader-1 Degrader / Unkown
HY-151441 LRRK2-IN-5 Inhibitor / Unkown
HY-172952 LRRK2-IN-17 Inhibitor / Unkown
HY-178797 PROTAC LRRK2 Degrader-3 Degrader / Unkown
HY-161571 LRRK2-IN-13 Inhibitor / Unkown
HY-156167 LRRK2-IN-10 Inhibitor / Unkown
HY-165543 SRI-29132 Inhibitor / Unkown
HY-134562 PF-06371900 Inhibitor 99.43% Unkown
HY-180320 Lu AF58786 Inhibitor / Unkown
HY-144074 LRRK2-IN-4 Inhibitor / Unkown
HY-161570 LRRK2-IN-12 Inhibitor / Unkown
HY-153103 LRRK2/NUAK1/TYK2-IN-1 Inhibitor / Unkown
HY-175651 LRRK2-IN-20 Inhibitor / Unkown
HY-15800 CZC-25146 hydrochloride Inhibitor / Unkown
HY-149187 LRRK2-IN-9 Inhibitor / Unkown
HY-181046 Multi-kinase-IN-14 Inhibitor / Unkown
HY-P10636 Nictide / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens LRRK2 NCBI NCBI:120892