RBM47 - RNA binding motif protein 47 Gene

Also Known as NET18

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54502

About RBM47

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:40,423,280-40,630,852 (from NCBI)

This gene has 15 transcripts (splice variants), 203 orthologues and 36 paralogues. Broad expression in colon (RPKM 20.7), kidney (RPKM 20.0) and 22 other tissues.

Summary

Enables RNA binding activity. Predicted to act upstream of or within cytidine to uridine editing and hematopoietic progenitor cell differentiation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RBM47 Products (4)

mRNA Protein Name
NM_001098634.2 NP_001092104.1 RNA-binding protein 47 isoform a
NM_001371113.1 NP_001358042.1 RNA-binding protein 47 isoform a
NM_001371114.1 NP_001358043.1 RNA-binding protein 47 isoform c
NM_019027.4 NP_061900.2 RNA-binding protein 47 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
24038582 GOA
enables enzyme binding IPI
IPI: Inferred from physical interaction
24916387 GOA
enables enzyme-substrate adaptor activity IDA
IDA: Inferred from direct assay
24916387 GOA
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
34160127 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
24916387 GOA
Biological Process GO Annotation Evidence References Source
involved in 3'-UTR-mediated mRNA stabilization IDA
IDA: Inferred from direct assay
34160127 GOA
involved in cytidine to uridine editing IDA
IDA: Inferred from direct assay
24916387 GOA
involved in positive regulation of type I interferon-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
34160127 GOA
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
31358901 GOA
Cellular Component GO Annotation Evidence References Source
part of apolipoprotein B mRNA editing enzyme complex IDA
IDA: Inferred from direct assay
24916387 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
24916387 GOA
located in nucleus IDA
IDA: Inferred from direct assay
24038582 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RBM47 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (73 - 137)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (153 - 214)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (248 - 311)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 593 a.a.
Protein Preferred Names Protein Names

RNA-binding protein 47

RBM47 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RBM47 A0AV96 FAM22F Homo sapiens B7ZLH0
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 FAM22F Homo sapiens B7ZLH0
Validated Y2H
32296183
Intra
RBM47 A0AV96 FAM22F Homo sapiens B7ZLH0
Y2H Array
32296183
Intra
RBM47 A0AV96 PCBP3 Homo sapiens P57721-2
Validated Y2H
32296183
Intra
RBM47 A0AV96 ZNF385C Homo sapiens Q66K41-2
Validated Y2H
32296183
Intra
RBM47 A0AV96 RBM46 Homo sapiens Q8TBY0
Anti Tag CoIP
33961781
Intra
RBM47 A0AV96 RBFOX1 Homo sapiens Q9NWB1-5
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 RBFOX1 Homo sapiens Q9NWB1-5
Validated Y2H
32296183
Intra
RBM47 A0AV96 RBFOX1 Homo sapiens Q9NWB1-5
Y2H Array
32296183
Intra
RBM47 A0AV96 CELF5 Homo sapiens Q8N6W0
Validated Y2H
32296183
Intra
RBM47 A0AV96 CELF5 Homo sapiens Q8N6W0
Y2H Array
32296183
Intra
RBM47 A0AV96 CELF5 Homo sapiens Q8N6W0
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 C10orf55 Homo sapiens Q5SWW7
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 C10orf55 Homo sapiens Q5SWW7
Validated Y2H
32296183
Intra
RBM47 A0AV96 C10orf55 Homo sapiens Q5SWW7
Y2H Array
32296183
Intra
RBM47 A0AV96 CAMK2A Homo sapiens Q9UQM7
Validated Y2H
32296183
Intra
RBM47 A0AV96 CAMK2A Homo sapiens Q9UQM7
Y2H Array
32296183
Intra
RBM47 A0AV96 CAMK2A Homo sapiens Q9UQM7
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 PRR13 Homo sapiens Q9NZ81
Y2H Array
32296183
Intra
RBM47 A0AV96 PRR13 Homo sapiens Q9NZ81
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 PRR13 Homo sapiens Q9NZ81
Validated Y2H
32296183
Intra
RBM47 A0AV96 OTX2 Homo sapiens P32243-2
Y2H Array
32296183
Intra
RBM47 A0AV96 OTX2 Homo sapiens P32243-2
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 OTX2 Homo sapiens P32243-2
Validated Y2H
32296183
Intra
RBM47 A0AV96 C1orf94 Homo sapiens Q6P1W5
Y2H Prey Pooling
32296183
Intra
RBM47 A0AV96 C1orf94 Homo sapiens Q6P1W5
Y2H Array
32296183
Intra
RBM47 A0AV96 C1orf94 Homo sapiens Q6P1W5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11755 RBM47 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RBM47 VGNC VGNC:53198
Rattus norvegicus RBM47 RGD RGD:1359713
Bos taurus RBM47 VGNC VGNC:33804
Macaca mulatta RBM47 VGNC VGNC:76576
Felis catus RBM47 VGNC VGNC:64535
Mus musculus RBM47 MGD MGI:2384294