DDX49 - DEAD-box helicase 49 Gene

Also Known as Dbp8; R27090_2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54555

About DDX49

This gene has 14 transcripts (splice variants), 194 orthologues and 38 paralogues. Ubiquitous expression in testis (RPKM 13.3), bone marrow (RPKM 12.8) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in positive regulation of cell growth and regulation of rRNA stability. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DDX49 Products (1)

mRNA Protein Name
NM_019070.5 NP_061943.2 probable ATP-dependent RNA helicase DDX49

DDX49 Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (26 - 195)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (267 - 343)

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  • 483 a.a.
Protein Preferred Names Protein Names

probable ATP-dependent RNA helicase DDX49

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 49

DDX49 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DDX49 Q9Y6V7 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra
DDX49 Q9Y6V7 STX1A Homo sapiens Q16623
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03654 DDX49 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20907 Ddx49 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27424 Ddx49 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DDX49 VGNC VGNC:61411
Mus musculus DDX49 MGD MGI:2136689
Rattus norvegicus DDX49 RGD RGD:1311124
Bos taurus DDX49 VGNC VGNC:27971
Canis familiaris DDX49 VGNC VGNC:39861
Macaca mulatta DDX49 VGNC VGNC:71665
Others DDX49 NCBI